Read e-book online Biochemistry of Collagen PDF

By Karl. A. Piez (auth.), G. N. Ramachandran, A. H. Reddi (eds.)

ISBN-10: 1475746024

ISBN-13: 9781475746020

ISBN-10: 1475746040

ISBN-13: 9781475746044

Collagen is an engaging protein not just as a result of its ubiquitous prevalence in multicellular animals, but additionally due to its exact chemi­ cal constitution. because the principal constituent in bone, cartilage, pores and skin, tendon, and enamel, it isn't wonderful that collagen is of curiosity to anatomists, biochemists, biomedical engineers, mobilephone biologists, dermatolo­ gists, dental surgeons, leather-based chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a number of others. This e-book was once deliberate to supply an up to date finished survey of all features of biochemistry of collagen. the new discovery of genetically targeted collagens with tissue specificity has opened a brand new period in collagen biochemistry, and Karl Piez discusses this within the commencing bankruptcy on fundamental constitution. within the subsequent bankruptcy, Ramachandran and Rama­ krishnan take care of the molecular constitution of collagen, putting targeted emphasis at the conformational features of its polypeptide chains. persist with­ ing the honor of fundamental and secondary constitution of collagen, the 3-dimensional association of collagen molecules within the fibrils is roofed via Miller in bankruptcy three. Collagen is usually within the insoluble country within the dwelling organism end result of the cross-linking of person molecules, and Tanzer describes many of the points of this cross-linkage in bankruptcy four. The biosynthesis of collagen is mentioned intensive through Prockop and his colleagues.

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And Finch, j. , Jr:, 1976, The covalent structure of cartilage collagen. Amino acid sequence of the NH 2-terminal portion of the al(II) chain, Biochemistry (in press). Byers, P. , McKenney, K. , Lichtenstein, j. , and Martin, G. , 1974, Preparation of type III procollagen and collagen from rat skin, Biochemistry 13:5243. Chapman, j. , 1974, The staining pattern of collagen fibrils. 1. An analysis of electron micrographs, Conn. Tissue Res. 2: 137. Chapman, j. , and Hardcastle, R. , 1974, The staining pattern of collagen fibrils II.

250:7428. Kefalides, N. , 1973, Structure and biosynthesis of basement membranes, Int. Rev. Conn. Tissue Res. 6:63. Kefalides, N. , 1974, Selective cleavage of basement membrane proteins at the carboxyl peptide linkages of methionine and at the amino peptide linkages of cysteine residues, in: Proc. XXII nd Colloquium on Protides of Biological Fluids, Brugge, Belgium, Pergamon Press (in press). , 1961, Eigenschaften des Tropokollagen-Molekuls und deren Bedeutung fur die Fibrillenbildung, Z. Naturforsch.

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Biochemistry of Collagen by Karl. A. Piez (auth.), G. N. Ramachandran, A. H. Reddi (eds.)


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