By C. Stan Tsai
This publication offers an built-in remedy of the constitution and serve as of nucleic acids, proteins, and glycans, together with thorough insurance of proper computational biochemistry.
The textual content starts with an creation to the biomacromolecules, through dialogue of equipment of isolation and purification, physiochemical and biochemical homes, and structural features. the subsequent part of the ebook bargains with series research, research of conformation utilizing spectroscopy, chemical synthesis, and computational ways. the subsequent chapters talk about biomolecular interactions, enzyme motion, gene transmission, sign transduction, and biomacromolecular informatics. the writer concludes with providing the most recent findings in genomics, proteomics, glycomics, and biomacromolecular evolution.
This textual content is a useful source for examine pros wishing to maneuver into genomics, proteomics, and glycomics study. it's also priceless for college kids in biochemistry, molecular biology, bioengineering, biotechnology, and bioinformatics.
Read Online or Download Biomacromolecules. Intro to Structure, Function and Informatics PDF
Best biochemistry books
It's been eighty years because the topic of bacterial adhesion to surfaces was once first introduced forth, yet in basic terms within the final twenty years has the significance of this topic been well-known via clinical microbiologists. the truth that bacterial attachment to the host tissue is a prerequisite for an infection understandably ended in the wish that infections can be avoided via blocking off the adhesion of pathogenic micro organism.
Electron Paramagnetic Resonance (EPR) spectroscopy - additionally occasionally termed Electron Spin Resonance spectroscopy - has manifold power makes use of in biochemistry and drugs. The paramount value of EPR spectroscopy utilized to organic tissues and fluids is that it identifies the adjustments in redox techniques that give a contribution to sickness.
Additional resources for Biomacromolecules. Intro to Structure, Function and Informatics
The three covalent biomacromolecules share some similarities in their global structures but differ in their cellular functions and structural details. DNA is the carrier of genetic information, which must be faithfully duplicated and selectively transcribed so that each cell can synthesize the proteins it needs. RNA functions mainly in the transcription and translation of this information. In order that the nucleic acids may convey genetic information, a pattern or code must be incorporated in their chemical structure.
The rotations about a central bond B—C are described by torsion angles involving four atoms in sequence, A—B—C—D. 170 Note: Covalent radii for two atoms can be summed to give the interatomic distance. The van der Waals radii determine how closely molecules can pack. They are usually measured from the shortest distances that can exist between neighboring (and not covalently bonded) atoms in the crystalline state. 02 nm less than the sum of the van der Waals radii. 3 NONCOVALENT INTERACTIONS 5 projected bonds A—B and C—D when looking along the central bond in either direction.
Sequences of nucleotides in nucleic acids are written with one-letter symbols starting with the 5′-terminus at the left toward 3′-terminus at the right. Deoxyribonucleotides in DNA is preﬁxed with d. If it is not known whether a residue is A or G, the appropriate abbreviation for purine is R; Y is used for pyrimidine, C or T. 4. Special symbols (incompletely speciﬁed bases in restriction sequences) include: B for G/T/C (not A), D for A/G/T (not C), H for A,T,C (not G), V for A/G/C (not T) and N for A/C/G/T.
Biomacromolecules. Intro to Structure, Function and Informatics by C. Stan Tsai