Download e-book for iPad: Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids by Ben Shen (auth.), Dr. Finian J. Leeper, Prof. Dr. John C.

By Ben Shen (auth.), Dr. Finian J. Leeper, Prof. Dr. John C. Vederas (eds.)

ISBN-10: 3540665730

ISBN-13: 9783540665731

This ebook is the second one of 2 volumes that care for discovery of chemical pathways of biosynthesis of common items (secondary metabolites). quantity 1 coated using isotopes in biosynthetic examine and the formation of enzyme cofactors and diminished polyketides. This moment quantity describes biosynthesis of fragrant (unreduced) polyketides, enzymes liable for cyclization of terpenoids (isoprenoids), and biochemical iteration of chosen sessions of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). wisdom of the pathways and the suggestions to clarify them opens the door to combinatorial biosynthesis in addition to to the creation of particular pharmaceutical brokers using a mixture of chemistry, molecular biology and protein biochemistry.

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Shen B, Hutchinson CR (1993) Biochemistry 32:11,149 95. Shen B, Summers RG, Wendt-Pienkowski E, Hutchinson CR (1995) J Am Chem Soc 117:6811 96. Shen B, Hutchinson CR (1996) Proc Natl Acad Sci USA 93:6600 97. Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR (1993) J Bacteriol 174:1810 98. Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR (1993) J Bacteriol 175:7571 99. Zhang HI, He XG, Adefarati A, Gallucci J, Cole SP, Beale JM, Keller PJ, Chang CJ, Floss HG (1990) J Org Chem 55:1682 100.

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Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids by Ben Shen (auth.), Dr. Finian J. Leeper, Prof. Dr. John C. Vederas (eds.)


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