By Tim Storr
Increasing the efficiency of healing compounds, whereas restricting side-effects, is a typical target in medicinal chemistry. Ligands that successfully bind steel ions and in addition contain particular positive aspects to augment focusing on, reporting, and total efficacy are riding innovation in components of disorder analysis and therapy.
Ligand layout in Medicinal Inorganic Chemistry provides the state of the art in ligand layout for medicinal inorganic chemistry functions. every one person bankruptcy describes and explores the appliance of compounds that both aim a ailment website, or are activated by way of a disease-specific organic process.
Ligand layout is mentioned within the following areas:
- Platinum, Ruthenium, and Gold-containing anticancer agents
- Emissive metal-based optical probes
- Metal-based antimalarial agents
- Metal overload disorders
- Modulation of metal-protein interactions in neurodegenerative diseases
- Photoactivatable steel complexes and their use in biology and medicine
- Radiodiagnostic brokers and Magnetic Resonance Imaging (MRI) agents
- Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry
- Metalloprotein inhibitors
Ligand layout in Medicinal Inorganic Chemistry offers graduate scholars, commercial chemists and educational researchers with a launching pad for brand spanking new learn in medicinal chemistry.